GPI antibody (C-Term)

Catalog No. ABIN2788669

This Rabbit Polyclonal antibody specifically detects GPI in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse and Zebrafish (Danio rerio).

Quick Overview for GPI antibody (C-Term) (ABIN2788669)

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPI antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GPI Antibody

Binding Specificity: C-Term

Purpose: GPI Antibody - C-terminal region

Sequence: EALMRGKSTE EARKELQAAG KSPEDLERLL PHKVFEGNRP TNSIVFTKLT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against GPI. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GPI

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61089-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPI

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Alternative Name: GPI

Background:

Background Information: This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Gene Name: Glucose-6-phosphate isomerase

Alternative Symbols: AMF, NLK, PGI, PHI, GNPI, SA36, SA-36

Protein Name: Glucose-6-phosphate isomerase

Molecular Weight: 63kDa

Gene ID: 2821

NCBI Accession: NP_000166

UniProt: P06744