IL2 Receptor beta antibody (C-Term)
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- Target See all IL2 Receptor beta (IL2RB) Antibodies
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL2 Receptor beta antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QGYFFFHLPD ALEIEACQVY FTYDPYSEED PDEGVAGAPT GSSPQPLQPL
- Predicted Reactivity
- Human: 100%, Rat: 77%, Yeast: 100%
- Characteristics
- This is a rabbit polyclonal antibody against IL2RB. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product IL2RB Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 551 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- Alternative Name
- IL2RB (IL2RB Products)
- Synonyms
- IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
- Background
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The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Alias Symbols: CD122, P70-75, IL15RB
Protein Interaction Partner: ECM1, JAK1, SOCS3, LCK, NEDD4, HGS, UBC, EIF3B, STAT5B, SOCS1, CISH, STAT5A, IL15RA, SHC1, STAT1, IL15, SHB, JAK3, SYK, IL2RG, GNB2L1, PTPN6, PIK3R1, LYN, RAF1, IL2RA, IL2, FYN, GRB2, STAT3, JAK2,
Protein Size: 551 - Molecular Weight
- 58 kDa
- Gene ID
- 3560
- NCBI Accession
- NM_000878, NP_000869
- UniProt
- P14784
- Pathways
- JAK-STAT Signaling, Growth Factor Binding
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