UGDH antibody (C-Term)

Catalog No. ABIN2788735

This Rabbit Polyclonal antibody specifically detects UGDH in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Rabbit, Dog and Guinea Pig.

Quick Overview for UGDH antibody (C-Term) (ABIN2788735)

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGDH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UGDH Antibody

Binding Specificity: C-Term

Sequence: VLDGLHNELQ TIGFQIETIG KKVSSKRIPY APSGEIPKFS LQDPPNKKPK

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against UGDH. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 494 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UGDH

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Alternative Name: UGDH

Background: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.
Alias Symbols: GDH, UDP-GlcDH, UDPGDH, UGD
Protein Interaction Partner: UGDH, CIAO1, SUMO2, UBC, XPO5, MAT2B, RPUSD2, GORASP2, BOP1, RNASEH2A, ATG7, PDIA6, SNX1, PRKACA, ME1, MAT2A, GTF2A1, GARS, CTTN, BAG3, UGT1A1, RAD51, UBE2V1, TKT, ELAVL1, SIRT1, SIRT3, TERF2, AK5,
Protein Size: 494

Molecular Weight: 54 kDa

Gene ID: 7358

NCBI Accession: NM_003359, NP_003350

UniProt: O60701

Pathways: Glycosaminoglycan Metabolic Process