Prohibitin antibody (C-Term)

Catalog No. ABIN2788746

The Rabbit Polyclonal anti-Prohibitin antibody is suitable to detect Prohibitin in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Cow, Dog, Horse, Goat and Saccharomyces cerevisiae. It has been validated for WB and IHC.

Quick Overview for Prohibitin antibody (C-Term) (ABIN2788746)

Target: Prohibitin (PHB)

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Cow, Dog, Horse, Goat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prohibitin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Prohibitin Antibody

Binding Specificity: C-Term

Purpose: Phb Antibody - C-terminal region

Sequence: AKQVAQQEAE RARFVVEKAE QQKKAAIISA EGDSKAAELI ANSLATAGDG

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Phb. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61278-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Prohibitin

Target: Prohibitin (PHB)

Alternative Name: Phb

Background:

Background Information: Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. Phb may play a role in regulating mitochondrial respiration activity and in aging.

Gene Name: Prohibitin

Alternative Symbols: Bap32

Protein Name: Prohibitin

Molecular Weight: 30kDa

Gene ID: 18673

NCBI Accession: NP_032857

UniProt: P67778

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling