PPT1 antibody (C-Term)

Catalog No. ABIN2788801

This anti-PPT1 antibody is a Rabbit Polyclonal antibody detecting PPT1 in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for PPT1 antibody (C-Term) (ABIN2788801)

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPT1 Antibody

Binding Specificity: C-Term

Sequence: GQAKETIPLQ ETSLYTQDRL GLKEMDNAGQ LVFLATEGDH LQLSEEWFYA

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 77%, Rabbit: 92%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against PPT1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 306 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPT1

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Alternative Name: PPT1

Background: The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CLN1, INCL, PPT
Protein Interaction Partner: UBC, MDM2, GNAQ, TMEM9, NIT2, RIF1, NIPBL, SLC9A3R2, XRCC1, TCOF1, SGSH, FBXO6, MYC,
Protein Size: 306

Molecular Weight: 34 kDa

Gene ID: 5538

NCBI Accession: NM_000310, NP_000301

UniProt: P50897

Pathways: SARS-CoV-2 Protein Interactome