IRAK4 antibody (C-Term)
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- Target See all IRAK4 Antibodies
- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Cow, Horse, Sheep, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRAK4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TGLPAVDEHR EPQLLLDIKE EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS
- Predicted Reactivity
- Cow: 77%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Rat: 91%, Sheep: 77%
- Characteristics
- This is a rabbit polyclonal antibody against IRAK4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product IRAK4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 336 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
- Alternative Name
- IRAK4 (IRAK4 Products)
- Synonyms
- zgc:55553 antibody, IRAK4 antibody, ipd1 antibody, irak-4 antibody, ny-ran-64 antibody, ny-ren-64 antibody, ren64 antibody, irak4 antibody, IPD1 antibody, IRAK-4 antibody, NY-REN-64 antibody, REN64 antibody, 8430405M07Rik antibody, 9330209D03Rik antibody, interleukin 1 receptor associated kinase 4 antibody, interleukin-1 receptor-associated kinase 4 antibody, IRAK4 antibody, irak4 antibody, Irak4 antibody
- Background
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This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: IPD1, NY-REN-64, REN64, IRAK-4
Protein Interaction Partner: MYD88, IRAK1, IKBKG, SASH1, ARNT, TNFRSF13B, IL1RL1, TRAF6, PELI1, PELI2, IL1R1, MBP, HIST1H1A, HIST1H1T, HIST1H1B, HIST1H1E, HIST1H1D, HIST1H1C, EIF4EBP1, TIRAP, IRAK3, IRAK2, TLR4, TICAM2, TBPL1, PELI3, UBC,
Protein Size: 336 - Molecular Weight
- 36 kDa
- Gene ID
- 51135
- NCBI Accession
- NM_001145256, NP_001138728
- Pathways
- NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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