ARFGEF1 antibody (Middle Region)

Catalog No. ABIN2788869

The Rabbit Polyclonal anti-ARFGEF1 antibody is suitable to detect ARFGEF1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for ARFGEF1 antibody (Middle Region) (ABIN2788869)

Target: ARFGEF1 (ADP-Ribosylation Factor Guanine Nucleotide-Exchange Factor 1(brefeldin A-Inhibited) (ARFGEF1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARFGEF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARFGEF1 Antibody

Binding Specificity: Middle Region

Sequence: SDVLLDDIFA QLYWCVQQDN EQLARSGTNC LENVVILNGE KFTLEIWDKT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ARFGEF1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ARFGEF2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARFGEF1

Target: ARFGEF1 (ADP-Ribosylation Factor Guanine Nucleotide-Exchange Factor 1(brefeldin A-Inhibited) (ARFGEF1))

Alternative Name: ARFGEF1

Background: ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition.
Alias Symbols: BIG2, PVNH2, dJ1164I10.1
Protein Size: 702

Molecular Weight: 77 kDa

Gene ID: 10564

NCBI Accession: NM_006420, NP_006411

UniProt: Q9Y6D5

Pathways: Regulation of Actin Filament Polymerization, Regulation of Carbohydrate Metabolic Process