DOK7 antibody (C-Term)

Catalog No. ABIN2788906

The Rabbit Polyclonal anti-DOK7 antibody is suitable to detect DOK7 in samples from Human. It has been validated for WB.

Quick Overview for DOK7 antibody (C-Term) (ABIN2788906)

Target: DOK7 (Docking Protein 7 (DOK7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DOK7 Antibody

Binding Specificity: C-Term

Purpose: DOK7 Antibody - C-terminal region

Sequence: RAHYDTPRSL CLAPRDHSPP SQGSPGNSAA RDSGGQTSAG CPSGWLGTRR

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against DOK7. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61801-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DOK7

Target: DOK7 (Docking Protein 7 (DOK7))

Alternative Name: DOK7

Background:

Background Information: The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B.

Gene Name: Docking protein 7

Alternative Symbols: CMS10, CMS1B, FADS3, C4orf25

Protein Name: Protein Dok-7

Molecular Weight: 40kDa

Gene ID: 285489

NCBI Accession: NP_775931

UniProt: Q18PE1

Pathways: Skeletal Muscle Fiber Development