CARD10 antibody (C-Term)

Catalog No. ABIN2788932

This Rabbit Polyclonal antibody specifically detects CARD10 in WB. It exhibits reactivity toward Human, Cow, Guinea Pig, Horse, Rat, Dog and Rabbit.

Quick Overview for CARD10 antibody (C-Term) (ABIN2788932)

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Reactivity: Human, Cow, Guinea Pig, Horse, Rat, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CARD10 Antibody

Binding Specificity: C-Term

Sequence: RVSGRSPPGG PEPQDKGPDG LSFYGDRWSG AVVRRVLSGP GSARMEPREQ

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CARD10. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1032 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CARD10

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Alternative Name: CARD10

Background: The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B through BCL10.
Alias Symbols: BIMP1, CARMA3, MGC142219
Protein Interaction Partner: KLHL12, UBC, CARD10, BCL10, IKBKG, ATXN7,
Protein Size: 1032

Molecular Weight: 114 kDa

Gene ID: 29775

NCBI Accession: NM_000984, NP_000975

UniProt: P62750

Pathways: S100 Proteins