CHMP4A antibody (C-Term)

Catalog No. ABIN2788971

The Rabbit Polyclonal anti-CHMP4A antibody is suitable to detect CHMP4A in samples from Human, Cow, Rabbit and Rat. It has been validated for WB.

Quick Overview for CHMP4A antibody (C-Term) (ABIN2788971)

Target: CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))

Reactivity: Human, Cow, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP4A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHMP4A Antibody

Binding Specificity: C-Term

Purpose: CHMP4A Antibody - C-terminal region

Sequence: ELEQEELAQE LLNVGDKEEE PSVKLPSVPS THLPAGPAPK VDEDEEALKQ

Predicted Reactivity: Cow: 77%, Human: 100%, Rabbit: 92%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against CHMP4A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61976-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHMP4A

Target: CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))

Alternative Name: CHMP4A

Background:

Background Information: CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression

Gene Name: Charged multivesicular body protein 4A

Alternative Symbols: SNF7, CHMP4, SHAX2, CHMP4B, SNF7-1, VPS32A, HSPC134, VPS32-1, C14orf123

Protein Name: Charged multivesicular body protein 4a Ensembl ENSP00000324205

Molecular Weight: 29kDa

Gene ID: 29082

NCBI Accession: NP_054888

UniProt: Q14D22