POLR2A/RPB1 antibody (N-Term)
Quick Overview for POLR2A/RPB1 antibody (N-Term) (ABIN2788998)
Target
See all POLR2A/RPB1 (POLR2A) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- DNKFGVEQPE GDEDLTKEKG HGGCGRYQPR IRRSGLELYA EWKHVNEDSQ
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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Characteristics
- This is a rabbit polyclonal antibody against POLR2A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of human POLR2A
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anti-RNA Polymerase II Subunit RPB1 (POLR2A) (AA 1-260) antibody
POLR2A Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-RNA Polymerase II Subunit RPB1 (POLR2A) (AA 1-260) antibodyPOLR2A Reactivity: Human WB, IHC, IF, IP, ChIP Host: Rabbit Polyclonal unconjugated
anti-RNA Polymerase II Subunit RPB1 (POLR2A) (pSer5) antibodyPOLR2A Reactivity: Human WB, IF, ELISA, ChIP, FM, CUT&RUN Host: Mouse Monoclonal unconjugated
anti-RNA Polymerase II Subunit RPB1 (POLR2A) (pSer2) antibodyPOLR2A Reactivity: Human WB, IF, ELISA, ChIP, FM, CUT&RUN Host: Mouse Monoclonal unconjugated
anti-RNA Polymerase II Subunit RPB1 (POLR2A) (AA 10-321) antibodyPOLR2A Reactivity: Human, Mouse, Rat, Monkey WB, IHC, IF, ELISA, FACS, ICC Host: Rabbit Polyclonal unconjugated
anti-RNA Polymerase II Subunit RPB1 (POLR2A) (pSer2) antibodyPOLR2A Reactivity: Human WB, IHC, IF, ELISA, IP Host: Rabbit Monoclonal 2G1 unconjugated Recombinant Antibody
anti-RNA Polymerase II Subunit RPB1 (POLR2A) (AA 128-258) antibodyPOLR2A Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 1B1D8 unconjugated
anti-RNA Polymerase II Subunit RPB1 (POLR2A) (pSer5) antibodyPOLR2A Reactivity: Human, Mouse, Rat WB, IHC, IF, FACS Host: Mouse Monoclonal CTD4H8 unconjugated
anti-RNA Polymerase II Subunit RPB1 (POLR2A) (pSer5) antibodyPOLR2A Reactivity: Human, Saccharomyces cerevisiae WB, IHC, IF, FACS Host: Mouse Monoclonal CTD 8A7 unconjugated
anti-RNA Polymerase II Subunit RPB1 (POLR2A) (Internal Region) antibodyPOLR2A Reactivity: Human, Mouse, Rat WB, IHC, IF, ELISA, ICC Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
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Alternative Name
- POLR2A
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Background
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This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Alias Symbols: RPB1, RPO2, POLR2, POLRA, RPBh1, RPOL2, RpIILS, hsRPB1, hRPB220
Protein Size: 566 -
Molecular Weight
- 62 kDa
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Gene ID
- 5430
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NCBI Accession
- NM_000937, NP_000928
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UniProt
- Q6NX41
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Pathways
- Regulatory RNA Pathways
Target
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