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CFHR1 antibody (C-Term)

CFHR1 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Horse, Pig, Sheep WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789086
  • Target See all CFHR1 Antibodies
    CFHR1 (Complement Factor H-Related 1 (CFHR1))
    Binding Specificity
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Rabbit, Cow, Horse, Pig, Sheep
    Host
    • 26
    • 5
    • 1
    Rabbit
    Clonality
    • 30
    • 2
    Polyclonal
    Conjugate
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CFHR1 antibody is un-conjugated
    Application
    • 20
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    FGDEEVMCLN GNWTEPPQCK DSTGKCGPPP PIDNGDITSF PLSVYAPASS
    Predicted Reactivity
    Cow: 100%, Horse: 77%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 100%, Rat: 100%, Sheep: 85%
    Characteristics
    This is a rabbit polyclonal antibody against CFHR1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product CFHR1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 330 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CFHR1 (Complement Factor H-Related 1 (CFHR1))
    Alternative Name
    CFHR1 (CFHR1 Products)
    Synonyms
    AI194696 antibody, CFHRB antibody, Cfhl1 antibody, CFHL antibody, CFHL1 antibody, CFHL1P antibody, CFHR1P antibody, FHR1 antibody, H36-1 antibody, H36-2 antibody, HFL1 antibody, HFL2 antibody, complement factor H-related 1 antibody, complement factor H-related protein 1 antibody, complement factor H related 1 antibody, Cfhr1 antibody, LOC735590 antibody, LOC746429 antibody, CFHR1 antibody
    Background
    This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
    Alias Symbols: CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2, MGC104329
    Protein Interaction Partner: PRDX4, LBP, APOA1, CFH,
    Protein Size: 330
    Molecular Weight
    36 kDa
    Gene ID
    3078
    NCBI Accession
    NM_002113, NP_002104
    UniProt
    Q03591
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