CFHR1 antibody (C-Term)

Catalog No. ABIN2789086

The Rabbit Polyclonal anti-CFHR1 antibody (ABIN2789086) specifically detects CFHR1 in WB. The antibody is reactive with Human, Rat, Mouse, Rabbit, Cow, Horse, Pig and Sheep samples.

Quick Overview for CFHR1 antibody (C-Term) (ABIN2789086)

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Horse, Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFHR1 Antibody

Binding Specificity: C-Term

Purpose: CFHR1 Antibody - C-terminal region

Sequence: FGDEEVMCLN GNWTEPPQCK DSTGKCGPPP PIDNGDITSF PLSVYAPASS

Predicted Reactivity: Cow: 100%, Horse: 77%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 100%, Rat: 100%, Sheep: 85%

Characteristics: This is a rabbit polyclonal antibody against CFHR1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62262-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CFHR1

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Alternative Name: CFHR1

Background:

Background Information: This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Gene Name: Complement factor H-related 1

Alternative Symbols: H36, CFHL, FHR1, HFL1, HFL2, CFHL1, FHR-1, H36-1, H36-2, CFHL1P, CFHR1P

Protein Name: Complement factor H-related protein 1

Molecular Weight: 36kDa

Gene ID: 3078

NCBI Accession: NP_002104

UniProt: Q03591