EDEM3 antibody (C-Term)

Catalog No. ABIN2789164

Product Details anti-EDEM3 Antibody

Target: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Dog, Horse, Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDEM3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NAASISPSEQ TSNPTENHET TNLNGECTDL DNQLQEQSET EEDSNPNVSW

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EDEM3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 889 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EDEM3

Target: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Alternative Name: EDEM3 (EDEM3 Products)

Synonyms: RGD1561496 antibody, C1orf22 antibody, 2310050N11Rik antibody, ER degradation enhancing alpha-mannosidase like protein 3 antibody, ER degradation enhancer, mannosidase alpha-like 3 L homeolog antibody, ER degradation enhancer, mannosidase alpha-like 3 antibody, Edem3 antibody, EDEM3 antibody, edem3.L antibody, edem3 antibody

Background: Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER.
Alias Symbols: C1orf22
Protein Interaction Partner: env, FBXO6, UBC, Zwint,
Protein Size: 889

Molecular Weight: 98 kDa

Gene ID: 80267

NCBI Accession: NM_001039508, NP_001034597

Pathways: SARS-CoV-2 Protein Interactome