MRPL3 antibody (N-Term)

Catalog No. ABIN2789212

Product Details anti-MRPL3 Antibody

Target: MRPL3 (Mitochondrial Ribosomal Protein L3 (MRPL3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MPLWTKDGQK HVVTLLQVQD CHVLKYTSKE NCNGKMATLS VGGKTVSRFR

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MRPL3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 348 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL3

Target: MRPL3 (Mitochondrial Ribosomal Protein L3 (MRPL3))

Alternative Name: MRPL3 (MRPL3 Products)

Synonyms: COXPD9 antibody, MRL3 antibody, RPML3 antibody, GB13776 antibody, 2010320L16Rik antibody, 5930422H18Rik antibody, AA407889 antibody, mrpl3 antibody, fj61d01 antibody, wu:fj61d01 antibody, zgc:66423 antibody, mitochondrial ribosomal protein L3 antibody, 39S ribosomal protein L3, mitochondrial antibody, mitochondrial 54S ribosomal protein YmL3 antibody, mitochondrial ribosomal protein L3 S homeolog antibody, MRPL3 antibody, LOC552676 antibody, Mrpl3 antibody, mrpl3.S antibody, mrpl3 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q.
Alias Symbols: MRL3, RPML3
Protein Interaction Partner: UBC, MRPS27, mug82, ICT1, C1QBP, MRPL55, MRPL10, MRPL52, MRPL9, MRPL41, MRPS9, MRPL17, MRPL39, MRPL4, MRPL13, MRPL42, MRPL46, MRPL19, RPS18, RPS15, MRPL12, MRPL23, NDUFS3, APP, CAND1,
Protein Size: 348

Molecular Weight: 38 kDa

Gene ID: 11222

NCBI Accession: NM_007208, NP_009139

UniProt: P09001