SLAMF1 antibody (Middle Region)
Quick Overview for SLAMF1 antibody (Middle Region) (ABIN2789221)
Target
See all SLAMF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- QVSPPEIKVL NKTQENENGT CSLLLACTVK KGDHVTYSWS DEAGTHLLSR
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Predicted Reactivity
- Cow: 77%, Dog: 85%, Goat: 77%, Guinea Pig: 80%, Horse: 85%, Human: 100%, Mouse: 87%, Pig: 100%, Rabbit: 80%, Rat: 93%, Sheep: 77%
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Characteristics
- This is a rabbit polyclonal antibody against Slamf1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Mouse Slamf1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
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Alternative Name
- Slamf1
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Background
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Slamf1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Alias Symbols: 4933415F16, AA177906, CD150, CDw150, ESTM51, IPO-3, Slam
Protein Interaction Partner: Sh2d1b1, Sh2d1b2, Sh2d1a,
Protein Size: 343 -
Molecular Weight
- 38 kDa
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Gene ID
- 27218
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NCBI Accession
- NM_013730, NP_038758
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UniProt
- Q9QUM4
Target
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