The Rabbit Polyclonal anti-SLAMF1 antibody (ABIN2789221) specifically detects SLAMF1 in WB.
The antibody is reactive with Human, Mouse, Rat, Pig, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit and Sheep samples.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
SLAMF1
(Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
Alternative Name
Slamf1
Background
Slamf1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. Alias Symbols: 4933415F16, AA177906, CD150, CDw150, ESTM51, IPO-3, Slam Protein Interaction Partner: Sh2d1b1, Sh2d1b2, Sh2d1a, Protein Size: 343