MRPL46 antibody (C-Term)

Catalog No. ABIN2789278

The Rabbit Polyclonal anti-MRPL46 antibody is suitable to detect MRPL46 in samples from Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse and Rabbit. It has been validated for WB.

Quick Overview for MRPL46 antibody (C-Term) (ABIN2789278)

Target: MRPL46 (Mitochondrial Ribosomal Protein L46 (MRPL46))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL46 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL46 Antibody

Binding Specificity: C-Term

Purpose: MRPL46 Antibody - C-terminal region

Sequence: KVFFFKALLL TGDFSQAGNK GHHVWVTKDE LGDYLKPKYL AQVRRFVSDL

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 77%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against MRPL46. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62872-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL46

Target: MRPL46 (Mitochondrial Ribosomal Protein L46 (MRPL46))

Alternative Name: MRPL46

Background:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

Gene Name: Mitochondrial ribosomal protein L46

Alternative Symbols: LIECG2, P2ECSL, C15orf4

Protein Name: 39S ribosomal protein L46, mitochondrial

Molecular Weight: 31kDa

Gene ID: 26589

NCBI Accession: NP_071446

UniProt: Q9H2W6