MRPL46 antibody (C-Term)

Catalog No. ABIN2789278

Product Details anti-MRPL46 Antibody

Target: MRPL46 (Mitochondrial Ribosomal Protein L46 (MRPL46))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL46 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KVFFFKALLL TGDFSQAGNK GHHVWVTKDE LGDYLKPKYL AQVRRFVSDL

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 77%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against MRPL46. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 279 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL46

Target: MRPL46 (Mitochondrial Ribosomal Protein L46 (MRPL46))

Alternative Name: MRPL46 (MRPL46 Products)

Synonyms: CG13922 antibody, Dmel\\CG13922 antibody, MRP-L46 antibody, DKFZp469F1933 antibody, C15orf4 antibody, LIECG2 antibody, P2ECSL antibody, 3110052F15Rik antibody, C80107 antibody, mitochondrial ribosomal protein L46 antibody, 39S ribosomal protein L46, mitochondrial antibody, mRpL46 antibody, LOC413989 antibody, MRPL46 antibody, mrpl46 antibody, Mrpl46 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Alias Symbols: C15orf4, LIECG2, MGC22762, P2ECSL
Protein Interaction Partner: NEDD1, NPM1, C1QBP, EIF3F, EIF3A, ATP6V0A1, MARCKSL1, MRPL4, MRPL3, SLC25A13, FUBP1, UBC, ICT1,
Protein Size: 279

Molecular Weight: 31 kDa

Gene ID: 26589

NCBI Accession: NM_022163, NP_071446

UniProt: Q9H2W6