CD80 antibody (C-Term)

Catalog No. ABIN2789329

The Rabbit Polyclonal anti-CD80 antibody has been validated for WB. It is suitable to detect CD80 in samples from Human and Pig.

Quick Overview for CD80 antibody (C-Term) (ABIN2789329)

Target: CD80

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD80 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD80 Antibody

Binding Specificity: C-Term

Sequence: IKYGHLRVNQ TFNWNTTKQE HFPDNLLPSW AITLISVNGI FVICCLTYCF

Predicted Reactivity: Human: 100%, Pig: 93%

Characteristics: This is a rabbit polyclonal antibody against CD80. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 288 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD80

Target: CD80

Alternative Name: CD80

Background: The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Alias Symbols: CD28LG, CD28LG1, LAB7, B7, BB1, B7-1, B7.1
Protein Interaction Partner: CD274, NGFR, CTLA4, CD28, CD86, CD80,
Protein Size: 288

Molecular Weight: 29 kDa

Gene ID: 941

NCBI Accession: NM_005191, NP_005182

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints