CD80 antibody (C-Term)

Catalog No. ABIN2789329

The Rabbit Polyclonal anti-CD80 antibody is suitable to detect CD80 in samples from Human and Pig. It has been validated for WB.

Quick Overview for CD80 antibody (C-Term) (ABIN2789329)

Target: CD80

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD80 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD80 Antibody

Binding Specificity: C-Term

Purpose: CD80 Antibody - C-terminal region

Sequence: IKYGHLRVNQ TFNWNTTKQE HFPDNLLPSW AITLISVNGI FVICCLTYCF

Predicted Reactivity: Human: 100%, Pig: 93%

Characteristics: This is a rabbit polyclonal antibody against CD80. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62996-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD80

Target: CD80

Alternative Name: CD80

Background:

Background Information: The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.

Gene Name: CD80 Molecule

Alternative Symbols: B7, BB1, B7-1, B7.1, LAB7, CD28LG, CD28LG1

Protein Name: T-lymphocyte activation antigen CD80

Molecular Weight: 29kDa

Gene ID: 941

NCBI Accession: NP_005182

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints