CCKBR antibody (C-Term)

Catalog No. ABIN2789413

Product Details anti-CCKBR Antibody

Target: CCKBR (Cholecystokinin B Receptor (CCKBR))

Binding Specificity: C-Term

Reactivity: Human, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCKBR antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GRCRPETGAV GEDSDGCYVQ LPRSRPALEL TALTAPGPGS GSRPTQAKLL

Predicted Reactivity: Guinea Pig: 79%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against CCKBR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 447 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCKBR

Target: CCKBR (Cholecystokinin B Receptor (CCKBR))

Alternative Name: CCKBR (CCKBR Products)

Synonyms: CCKBR antibody, LOC100232835 antibody, CCK-B antibody, CCK2R antibody, GASR antibody, Cck2r antibody, Cholrec antibody, CCKR-2 antibody, CCK-BR antibody, CCK2-R antibody, CCK-CHR antibody, cholecystokinin B receptor antibody, cholecystokinin receptor-like antibody, CCKBR antibody, LOC100232835 antibody, Cckbr antibody

Background: This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
Alias Symbols: CCK-B, CCK2R, GASR
Protein Interaction Partner: NTM, ADRB2, ATP13A2, PTPN11, CCKBR, CCKAR, CCK,
Protein Size: 447

Molecular Weight: 49 kDa

Gene ID: 887

NCBI Accession: NM_176875, NP_795344

UniProt: P32239

Pathways: Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour