GP5 antibody (C-Term)

Catalog No. ABIN2789435

This Rabbit Polyclonal antibody specifically detects GP5 in WB. It exhibits reactivity toward Human.

Quick Overview for GP5 antibody (C-Term) (ABIN2789435)

Target: GP5 (Glycoprotein V (Platelet) (GP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GP5 Antibody

Binding Specificity: C-Term

Purpose: GP5 Antibody - C-terminal region

Sequence: PNSSEPWVWA QPVTTGKGQD HSPFWGFYFL LLAVQAMITV IIVFAMIKIG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GP5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63287-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GP5

Target: GP5 (Glycoprotein V (Platelet) (GP5))

Alternative Name: GP5

Background:

Background Information: Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain and a beta chain, that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome, a bleeding disorder.

Gene Name: Glycoprotein V (platelet)

Alternative Symbols: GPV, CD42d

Protein Name: Platelet glycoprotein V

Molecular Weight: 62kDa

Gene ID: 2814

NCBI Accession: NP_004479

UniProt: P40197