GP5 antibody (C-Term)

Catalog No. ABIN2789435

Product Details anti-GP5 Antibody

Target: GP5 (Glycoprotein V (Platelet) (GP5))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GP5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PNSSEPWVWA QPVTTGKGQD HSPFWGFYFL LLAVQAMITV IIVFAMIKIG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GP5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 560 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GP5

Target: GP5 (Glycoprotein V (Platelet) (GP5))

Alternative Name: GP5 (GP5 Products)

Synonyms: lib antibody, GPV antibody, PLGPV antibody, CD42d antibody, glycoprotein V platelet L homeolog antibody, glycoprotein V platelet antibody, glycoprotein 5 (platelet) antibody, glycoprotein V (platelet) antibody, gp5.L antibody, GP5 antibody, Gp5 antibody

Background: Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain and a beta chain, that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome, a bleeding disorder.
Alias Symbols: CD42d
Protein Interaction Partner: YWHAZ, GP1BA, F2,
Protein Size: 560

Molecular Weight: 62 kDa

Gene ID: 2814

NCBI Accession: NM_004488, NP_004479

UniProt: P40197