PINK1 antibody (N-Term)

Catalog No. ABIN2789443

The Rabbit Polyclonal anti-PINK1 antibody has been validated for WB and IHC. It is suitable to detect PINK1 in samples from Human, Mouse, Rat, Guinea Pig, Rabbit, Cow and Horse.

Quick Overview for PINK1 antibody (N-Term) (ABIN2789443)

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PINK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PINK1 Antibody

Binding Specificity: N-Term

Sequence: GCAGPCGRAV FLAFGLGLGL IEEKQAESRR AVSACQEIQA IFTQKSKPGP

Predicted Reactivity: Cow: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PINK1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 581 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Alternative Name: PINK1

Background: This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.
Alias Symbols: BRPK, FLJ27236, PARK6
Protein Interaction Partner: IMMT, RHOT2, MCL1, BCL2L2, BCL2L1, UBC, BAG2, CRLS1, FBXO7, SARM1, RB1CC1, TOMM20, VIM, TRAF6, HSPA1B, HSPA1A, PARK2, HSP90AA1, TOLLIP, MAP3K7, IRAK1, RICTOR, SENP8, MAPKAP1, COPS8, UBE2M, AKT1, NEDD8, PINK1, TOMM22, RHOT1, HTRA2, PARK7, CDC37, TOMM40, TO
Protein Size: 581

Molecular Weight: 63 kDa

Gene ID: 65018

NCBI Accession: NM_032409, NP_115785

UniProt: Q9BXM7

Pathways: Autophagy