SOS1 antibody (N-Term)

Catalog No. ABIN2789455

The Rabbit Polyclonal anti-SOS1 antibody has been validated for WB. It is suitable to detect SOS1 in samples from Human, Mouse, Rat, Horse, Rabbit, Dog, Cow and Guinea Pig.

Quick Overview for SOS1 antibody (N-Term) (ABIN2789455)

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOS1 Antibody

Binding Specificity: N-Term

Sequence: YFELLKQLEE KSEDQEDKEC MKQAITALLN VQSGMEKICS KSLAKRRLSE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Sos1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Sos1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOS1

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Alternative Name: Sos1

Background: Sos1 promotes the exchange of Ras-bound GDP by GTP.
Alias Symbols: 4430401P03Rik, 9630010N06, AI449023
Protein Interaction Partner: Egfr, Spry3, Spry4, Spry2, Spry1, Crkl, Nck1, Mapk1, Mapk3, Csf1r, Grb2, Crk, Fyn, Fgr, Src, Pik3r1, Ptpn6,
Protein Size: 1319

Molecular Weight: 151 kDa

Gene ID: 20662

NCBI Accession: NM_009231, NP_033257

UniProt: Q62245

Pathways: RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling