SMN1 antibody (C-Term)
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- Target See all SMN1 Antibodies
- SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Pig, Rabbit, Horse, Guinea Pig, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SMN1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PPPPPICPDS LDDADALGSM LISWYMSGYH TGYYMGFRQN QKEGRCSHSL
- Predicted Reactivity
- Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 85%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against SMN1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of SMN1
- Top Product
- Discover our top product SMN1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 262 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))
- Alternative Name
- SMN1 (SMN1 Products)
- Synonyms
- SMN2 antibody, Smn antibody, SMN antibody, BCD541 antibody, GEMIN1 antibody, SMA antibody, SMA1 antibody, SMA2 antibody, SMA3 antibody, SMA4 antibody, SMA@ antibody, SMNT antibody, T-BCD541 antibody, TDRD16A antibody, AI849087 antibody, Gemin1 antibody, SMN1 antibody, QtsA-10002 antibody, fa12d01 antibody, smn antibody, wu:fa12d01 antibody, survival motor neuron protein antibody, survival of motor neuron 1, telomeric antibody, survival motor neuron 1 antibody, survival of motor neuron 2, centromeric antibody, survival motor neuron protein-like antibody, survival motor neuron antibody, LOC461829 antibody, Smn1 antibody, SMN1 antibody, SMN2 antibody, LOC100348318 antibody, SMN antibody, LOC100713418 antibody, LOC100065744 antibody, LOC102176643 antibody, smn1 antibody
- Background
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SMN1 localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein.
Alias Symbols: BCD541, SMA, SMA1, SMA2, SMA3, SMA4, SMA@, SMN, SMN2, SMNT, T-BCD541
Protein Interaction Partner: COPA, RNF2, BMI1, KDM1A, SMN1, RN7SL1, UBC, HDAC11, MIB1, GEMIN4, DICER1, DDX20, PAN2, RBFOX2, HNRNPUL1, IQCB1, UBL4A, SMN2, NOS2, vpr, GEMIN2, SRP68, SRP54, SRP19, SRP9, RNU2-1, RNU1-1, GEMIN5, MDC1, RBM25, COIL, SRSF5, HSPB1, CUL3, DDAH2, MAST2, SMC5, R
Protein Size: 262 - Molecular Weight
- 28 kDa
- Gene ID
- 6606
- NCBI Accession
- NM_022874, NP_075012
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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