CD82 antibody (C-Term)

Catalog No. ABIN2789464

The Rabbit Polyclonal anti-CD82 antibody (ABIN2789464) specifically detects CD82 in WB. The antibody is reactive with Human and Saccharomyces cerevisiae samples.

Quick Overview for CD82 antibody (C-Term) (ABIN2789464)

Target: CD82

Reactivity: Human, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD82 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD82 Antibody

Binding Specificity: C-Term

Purpose: CD82 Antibody - C-terminal region

Sequence: DYVQAQVKCC GWVSFYNWTD NAELMNRPEV TYPCSCEVKG EEDNSLSVRK

Predicted Reactivity: Human: 100%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against CD82. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63361-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD82

Target: CD82

Alternative Name: CD82

Background:

Background Information: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: CD82 Molecule

Alternative Symbols: R2, 4F9, C33, IA4, ST6, GR15, KAI1, SAR2, TSPAN27

Protein Name: CD82 antigen

Molecular Weight: 29kDa

Gene ID: 3732

NCBI Accession: NP_002222

UniProt: P27701

Pathways: p53 Signaling