DMC1 antibody (N-Term)

Catalog No. ABIN2789481

The Rabbit Polyclonal anti-DMC1 antibody (ABIN2789481) specifically detects DMC1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Goat, Guinea Pig, Saccharomyces cerevisiae and Zebrafish (Danio rerio) samples.

Quick Overview for DMC1 antibody (N-Term) (ABIN2789481)

Target: DMC1 (DNA Meiotic Recombinase 1 (DMC1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Goat, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DMC1 Antibody

Binding Specificity: N-Term

Purpose: DMC1 Antibody - N-terminal region

Sequence: GIQMTTRRAL CNVKGLSEAK VDKIKEAANK LIEPGFLTAF EYSEKRKMVF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against DMC1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63397-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DMC1

Target: DMC1 (DNA Meiotic Recombinase 1 (DMC1))

Alternative Name: DMC1

Background:

Background Information: The protein encoded by this gene is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this gene is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes. Alternative splice variants of this gene have been described but their full-length nature has not been determined.

Gene Name: DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)

Alternative Symbols: DMC1H, LIM15, dJ199H16.1

Protein Name: Meiotic recombination protein DMC1/LIM15 homolog

Molecular Weight: 37kDa

Gene ID: 11144

NCBI Accession: NP_008999

UniProt: Q14565