Cyclin B2 antibody (N-Term)

Catalog No. ABIN2789489

This Rabbit Polyclonal antibody specifically detects Cyclin B2 in WB. It exhibits reactivity toward Human, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for Cyclin B2 antibody (N-Term) (ABIN2789489)

Target: Cyclin B2 (CCNB2)

Reactivity: Human, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin B2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin B2 Antibody

Binding Specificity: N-Term

Sequence: IGNRVTTRAA QVAKKAQNTK VPVQPTKTTN VNKQLKPTAS VKPVQMEKLA

Predicted Reactivity: Cow: 83%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against CCNB2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 398 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cyclin B2

Target: Cyclin B2 (CCNB2)

Alternative Name: CCNB2

Background: Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
Alias Symbols: HsT17299
Protein Interaction Partner: CKS2, CKS1B, CDK1, CDK2, MCM2, CDKN1A, ATR, UBC, tat, TSPYL2, TGFBR2,
Protein Size: 398

Molecular Weight: 45 kDa

Gene ID: 9133

NCBI Accession: NM_004701, NP_004692

UniProt: O95067

Pathways: Cell Division Cycle, M Phase