IL13 Receptor alpha 1 antibody (N-Term)

Catalog No. ABIN2789491

The Rabbit Polyclonal anti-IL13 Receptor alpha 1 antibody has been validated for WB. It is suitable to detect IL13 Receptor alpha 1 in samples from Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Pig and Sheep.

Quick Overview for IL13 Receptor alpha 1 antibody (N-Term) (ABIN2789491)

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL13 Receptor alpha 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL13 Receptor alpha 1 Antibody

Binding Specificity: N-Term

Sequence: VSVENLCTVI WTWNPPEGAS SNCSLWYFSH FGDKQDKKIA PETRRSIEVP

Predicted Reactivity: Cow: 92%, Dog: 85%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 100%, Rat: 86%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against IL13RA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of IL13RA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 427 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL13 Receptor alpha 1

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Alternative Name: IL13RA1

Background: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Alias Symbols: CD213A1, IL-13Ra, NR4
Protein Interaction Partner: UBC, IL2RG, TMEM39B, ELAVL1, TRAF3IP1, DLG4, TYK2, IL4R, IL13,
Protein Size: 427

Molecular Weight: 47 kDa

Gene ID: 3597

NCBI Accession: NM_001560, NP_001551

UniProt: P78552

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response