IL13 Receptor alpha 1 antibody (AA 22-343)

Catalog No. ABIN7193280

The Mouse Monoclonal anti-IL13 Receptor alpha 1 antibody (Clone 8A3E3) (ABIN7193280) specifically detects IL13 Receptor alpha 1 in WB, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for IL13 Receptor alpha 1 antibody (AA 22-343) (ABIN7193280)

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL13 Receptor alpha 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 8A3E3

Product Details anti-IL13 Receptor alpha 1 Antibody

Binding Specificity: AA 22-343

Purpose: CD213A1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD213A1 (AA: 22-343) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for IL13 Receptor alpha 1

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Alternative Name: CD213A1

Background:

The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

Molecular Weight: 48.8 kDa

Gene ID: 3597

UniProt: P78552

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response