CD1e antibody (C-Term)

Catalog No. ABIN2789492

The Rabbit Polyclonal anti-CD1e antibody is suitable to detect CD1e in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Sheep. It has been validated for WB.

Quick Overview for CD1e antibody (C-Term) (ABIN2789492)

Target: CD1e

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1e antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD1e Antibody

Binding Specificity: C-Term

Purpose: CD1E Antibody - C-terminal region

Sequence: WVMWMRGEQE QRGTQRGDVL PNADETWWIF HLSHPDLFDC DSYPGHIGCS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 79%, Sheep: 79%

Characteristics: This is a rabbit polyclonal antibody against CD1E. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD1E

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63420-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD1e

Target: CD1e

Alternative Name: CD1E

Background:

Background Information: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found, however, their biological validity has not been determined.

Gene Name: CD1b molecule

Alternative Symbols: R2, CD1A

Protein Name: T-cell surface glycoprotein CD1e, membrane-associated

Molecular Weight: 31kDa

Gene ID: 913

UniProt: P15812