AASS antibody (C-Term)

Catalog No. ABIN2789499

The Rabbit Polyclonal anti-AASS antibody is suitable to detect AASS in samples from Human, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for AASS antibody (C-Term) (ABIN2789499)

Target: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AASS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AASS Antibody

Binding Specificity: C-Term

Sequence: HHHLVRKTDA VYDPAEYDKH PERYISRFNT DIAPYTTCLI NGIYWEQNTP

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against AASS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human AASS

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AASS

Target: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Alternative Name: AASS

Background: This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
Alias Symbols: LKRSDH, LORSDH, LKR/SDH
Protein Size: 511

Molecular Weight: 56 kDa

Gene ID: 10157

NCBI Accession: NM_005763, NP_005754

UniProt: Q9UDR5

Pathways: SARS-CoV-2 Protein Interactome