PTPRT antibody (AA 200-280)

Catalog No. ABIN7230850

The Rabbit Polyclonal anti-PTPRT antibody is suitable to detect PTPRT in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for PTPRT antibody (AA 200-280) (ABIN7230850)

Target: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRT antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-PTPRT Antibody

Binding Specificity: AA 200-280

Purpose: Rabbit Anti-PTPRT Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PTPRT protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PTPRT protein at AA range: 200-280

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PTPRT

Target: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Alternative Name: PTPRT

Background: Receptor-type tyrosine-protein phosphatase T, R-PTP-T, Receptor-type tyrosine-protein phosphatase rho, RPTP-rhoThe protein encoded by PTPRT is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRT possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of PTPRT suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of PTPRT, which encode distinct proteins, have been reported.

Molecular Weight: 158kD

Gene ID: 11122

UniProt: O14522