FYB antibody (C-Term)

Catalog No. ABIN2789512

This Rabbit Polyclonal antibody specifically detects FYB in WB. It exhibits reactivity toward Human, Mouse, Dog and Horse.

Quick Overview for FYB antibody (C-Term) (ABIN2789512)

Target: FYB (FYN-Binding Protein (FYB))

Reactivity: Human, Mouse, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FYB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FYB Antibody

Binding Specificity: C-Term

Sequence: MGDEVYDDVD TSDFPVSSAE MSQGTNVGKA KTEEKDLKKL KKQEKEEKDF

Predicted Reactivity: Dog: 100%, Horse: 79%, Human: 100%, Mouse: 75%

Characteristics: This is a rabbit polyclonal antibody against FYB. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 829 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FYB

Target: FYB (FYN-Binding Protein (FYB))

Alternative Name: FYB

Background: The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADAP, PRO0823, SLAP-130
Protein Interaction Partner: UBC, Mbp, LCP2, FYN, FASLG, CBL, CARD11, BCL10, MAP3K7, PRKCQ, ENAH, EVL, SKAP2, SKAP1, CBLB, BCAR1, VASP, SH2D1A, WAS, SRC,
Protein Size: 829

Molecular Weight: 96 kDa

Gene ID: 2533

NCBI Accession: NM_199335, NP_955367

UniProt: E9PBV9

Pathways: TCR Signaling, Protein targeting to Nucleus