CD151 antibody (C-Term)

Catalog No. ABIN2789524

The Rabbit Polyclonal anti-CD151 antibody (ABIN2789524) specifically detects CD151 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Pig samples.

Quick Overview for CD151 antibody (C-Term) (ABIN2789524)

Target: CD151

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD151 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CD151 Antibody

Binding Specificity: C-Term

Purpose: CD151 Antibody - C-terminal region

Sequence: HCCGSNNSQD WRDSEWIRSQ EAGGRVVPDS CCKTVVALCG QRDHASNIYK

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CD151. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63500-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD151

Target: CD151

Alternative Name: CD151

Background:

Background Information: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

Gene Name: CD151 Molecule (Raph blood group)

Alternative Symbols: GP27, MER2, RAPH, SFA1, PETA-3, TSPAN24

Protein Name: CD151 antigen

Molecular Weight: 28kDa

Gene ID: 977

NCBI Accession: NP_620599

UniProt: P48509