CD207 antibody (C-Term)

Catalog No. ABIN2789525

Product Details anti-CD207 Antibody

Target: CD207 (CD207 Molecule, Langerin (CD207))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Pig, Guinea Pig, Horse, Cow, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD207 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC

Predicted Reactivity: Cow: 92%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 83%, Rabbit: 83%, Rat: 83%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against CD207. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 328 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Alternative Name: CD207 (CD207 Products)

Synonyms: CD207 antibody, CLEC4K antibody, RGD1565913 antibody, CD207 molecule antibody, CD207 antigen antibody, CD207 antibody, Cd207 antibody

Background: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Alias Symbols: CLEC4K
Protein Interaction Partner: UBC,
Protein Size: 328

Molecular Weight: 36 kDa

Gene ID: 50489

NCBI Accession: NM_015717, NP_056532

UniProt: Q9UJ71