MCHR1 antibody (N-Term)

Catalog No. ABIN2789557

This Rabbit Polyclonal antibody specifically detects MCHR1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Pig, Guinea Pig, Horse and Rabbit.

Quick Overview for MCHR1 antibody (N-Term) (ABIN2789557)

Target: MCHR1 (Melanin-Concentrating Hormone Receptor 1 (MCHR1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCHR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MCHR1 Antibody

Binding Specificity: N-Term

Purpose: MCHR1 Antibody - N-terminal region

Sequence: SSARLWEQAT GTGWMDLEAS LLPTGPNASN TSDGPDNLTS AGSPPRTGSI

Predicted Reactivity: Cow: 86%, Dog: 92%, Guinea Pig: 81%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MCHR1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63587-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MCHR1

Target: MCHR1 (Melanin-Concentrating Hormone Receptor 1 (MCHR1))

Alternative Name: MCHR1

Background:

Background Information: The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.

Gene Name: Melanin-concentrating hormone receptor 1

Alternative Symbols: SLC1, GPR24, MCH1R, SLC-1, MCH-1R

Protein Name: G-protein coupled receptor 24 isoform 1 EMBL AAV98053.1

Molecular Weight: 32kDa

Gene ID: 2847

UniProt: Q5IFH6

Pathways: Feeding Behaviour