Integrin beta 3 antibody (N-Term)

Catalog No. ABIN2789560

Product Details anti-Integrin beta 3 Antibody

Target: Integrin beta 3 (ITGB3)

Binding Specificity: N-Term

Reactivity: Human, Rat, Cow, Dog, Rabbit, Sheep, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PLGSPRCDLK ENLLKDNCAP ESIEFPVSEA RVLEDRPLSD KGSGDSSQVT

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 92%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against ITGB3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 788 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: ITGB3 (ITGB3 Products)

Synonyms: BDPLT16 antibody, BDPLT2 antibody, CD61 antibody, GP3A antibody, GPIIIa antibody, GT antibody, INGRB3 antibody, integrin antibody, INTB3 antibody, GPIIIA antibody, cd61 antibody, gp3a antibody, itgb3 antibody, itgb3.2 antibody, itgb3.1 antibody, integrin subunit beta 3 antibody, integrin beta 3 antibody, integrin subunit beta 3 L homeolog antibody, integrin beta 3a antibody, integrin beta 3b antibody, ITGB3 antibody, Itgb3 antibody, itgb3.L antibody, itgb3a antibody, itgb3b antibody

Background: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Alias Symbols: CD61, GP3A, GPIIIa, GT, BDPLT2
Protein Interaction Partner: EPHA2, THBS1, SYK, TENC1, ANGPTL3, ITGB3BP, ITGA2B, PDPK1, NUMB, DAB1, DOK1, ILK, DAB2, PTK2B, PTK2, SHC1, EPS8, P2RY2, ITGAV, VTN, KDR, TGM2, SRC, THY1, TLN1, CD36, PDGFRA, ITGB3, PECAM1, PDGFRB, AKT1, FBLN2, ITGA5, FN1, FGG, FGA, NID1, COL1A2, CAPN1, CI
Protein Size: 788

Molecular Weight: 84 kDa

Gene ID: 3690

NCBI Accession: NM_000212, NP_000203

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex