Dopamine Receptor d1 antibody (N-Term)

Catalog No. ABIN2789562

This Rabbit Polyclonal antibody specifically detects Dopamine Receptor d1 in WB. It exhibits reactivity toward Human, Rat, Pig, Cow, Rabbit, Dog, Horse and Guinea Pig.

Quick Overview for Dopamine Receptor d1 antibody (N-Term) (ABIN2789562)

Target: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Reactivity: Human, Rat, Pig, Cow, Rabbit, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dopamine Receptor d1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Dopamine Receptor d1 Antibody

Binding Specificity: N-Term

Purpose: DRD1 Antibody - N-terminal region

Sequence: AAFILISVAW TLSVLISFIP VQLSWHKAKP TSPSDGNATS LAETIDNCDS

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DRD1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63609-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Dopamine Receptor d1

Target: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Alternative Name: DRD1

Background:

Background Information: This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events.

Gene Name: Dopamine receptor D1

Alternative Symbols: DADR, DRD1A

Protein Name: D(1A) dopamine receptor

Molecular Weight: 49kDa

Gene ID: 1812

NCBI Accession: NP_000785

UniProt: P21728

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity