IDUA antibody (C-Term)

Catalog No. ABIN2789573

This Rabbit Polyclonal antibody specifically detects IDUA in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Horse, Cow and Dog.

Quick Overview for IDUA antibody (C-Term) (ABIN2789573)

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDUA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IDUA Antibody

Binding Specificity: C-Term

Sequence: DPVAAAPRPL PAGGRLTLRP ALRLPSLLLV HVCARPEKPP GQVTRLRALP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 80%

Characteristics: This is a rabbit polyclonal antibody against IDUA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IDUA

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IDUA

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Alternative Name: IDUA

Background: This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).
Protein Interaction Partner: MPP3,
Protein Size: 675

Molecular Weight: 74 kDa

Gene ID: 3425

UniProt: P35475

Pathways: Glycosaminoglycan Metabolic Process