IDUA antibody (C-Term)
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- Target See all IDUA Antibodies
- IDUA (Iduronidase, alpha-L- (IDUA))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IDUA antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DPVAAAPRPL PAGGRLTLRP ALRLPSLLLV HVCARPEKPP GQVTRLRALP
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 80%
- Characteristics
- This is a rabbit polyclonal antibody against IDUA. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human IDUA
- Top Product
- Discover our top product IDUA Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IDUA (Iduronidase, alpha-L- (IDUA))
- Alternative Name
- IDUA (IDUA Products)
- Background
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This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).
Protein Interaction Partner: MPP3,
Protein Size: 675 - Molecular Weight
- 74 kDa
- Gene ID
- 3425
- UniProt
- P35475
- Pathways
- Glycosaminoglycan Metabolic Process
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