PALB2 antibody (N-Term)

Catalog No. ABIN2789617

This Rabbit Polyclonal antibody specifically detects PALB2 in WB. It exhibits reactivity toward Human.

Quick Overview for PALB2 antibody (N-Term) (ABIN2789617)

Target: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PALB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PALB2 Antibody

Binding Specificity: N-Term

Sequence: VLPGKSHPKR PNSQSQHTKT GLSSSILLYT PLNTVAPDDN DRPTTDMCSP

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PALB2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 590 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PALB2

Target: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Alternative Name: PALB2

Background: This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.
Alias Symbols: FANCN, PNCA3
Protein Interaction Partner: MORF4L1, RAD51, HNRNPC, BRCA2, BRCA1, ALB, PALB2, RBBP8, BACH1, MORF4L2, RAD51AP1, CAPN1,
Protein Size: 590

Molecular Weight: 64 kDa

Gene ID: 79728

NCBI Accession: NM_024675

UniProt: Q86YC2

Pathways: DNA Damage Repair