EPH Receptor B3 antibody (C-Term)

Catalog No. ABIN2789635

Product Details anti-EPH Receptor B3 Antibody

Target: EPH Receptor B3 (EPHB3)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QLQEQLPLIV GSATAGLVFV VAVVVIAIVC LRKQRHGSDS EYTEKLQQYI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against EPHB3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human EPHB3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 998 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EPH Receptor B3

Target: EPH Receptor B3 (EPHB3)

Alternative Name: EPHB3 (EPHB3 Products)

Synonyms: tck antibody, MGC83457 antibody, EPHB3 antibody, ETK2 antibody, HEK2 antibody, TYRO6 antibody, AW456895 antibody, Cek10 antibody, Etk2 antibody, MDK5 antibody, Sek4 antibody, Tyro6 antibody, CEK10 antibody, EK10 antibody, ek3 antibody, ephb3 antibody, fc62d03 antibody, rtk3 antibody, wu:fc62d03 antibody, zek3 antibody, EPH receptor B3 antibody, EPH receptor B3 L homeolog antibody, Eph receptor B3 antibody, eph receptor B3a antibody, Eph receptor tyrosine kinase antibody, EPHB3 antibody, ephb3.L antibody, ephb3 antibody, Ephb3 antibody, ephb3a antibody

Background: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members.
Alias Symbols: ETK2, HEK2, TYRO6
Protein Interaction Partner: UBC, NFRKB, GBE1, LNX1, EFNB3, EPHB3, RYK, CRK, MLLT4, RASA1, FYN,
Protein Size: 998

Molecular Weight: 107 kDa

Gene ID: 2049

NCBI Accession: NM_004443, NP_004434

UniProt: P54753

Pathways: RTK Signaling