EPH Receptor B3 antibody (C-Term)

Catalog No. ABIN2789635

The Rabbit Polyclonal anti-EPH Receptor B3 antibody is suitable to detect EPH Receptor B3 in samples from Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio) and Rabbit. It has been validated for WB.

Quick Overview for EPH Receptor B3 antibody (C-Term) (ABIN2789635)

Target: EPH Receptor B3 (EPHB3)

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio), Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPH Receptor B3 Antibody

Binding Specificity: C-Term

Purpose: EPHB3 Antibody - C-terminal region

Sequence: QLQEQLPLIV GSATAGLVFV VAVVVIAIVC LRKQRHGSDS EYTEKLQQYI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against EPHB3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human EPHB3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63815-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for EPH Receptor B3

Target: EPH Receptor B3 (EPHB3)

Alternative Name: EPHB3

Background:

Background Information: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members.

Gene Name: EPH receptor B3

Alternative Symbols: EK2, ETK2, HEK2, TYRO6

Protein Name: Ephrin type-B receptor 3

Molecular Weight: 107kDa

Gene ID: 2049

NCBI Accession: NP_004434

UniProt: P54753

Pathways: RTK Signaling