DIAPH1 antibody (C-Term)

Catalog No. ABIN2789663

The Rabbit Polyclonal anti-DIAPH1 antibody is suitable to detect DIAPH1 in samples from Human, Mouse, Rat, Dog, Cow, Rabbit and Pig. It has been validated for WB.

Quick Overview for DIAPH1 antibody (C-Term) (ABIN2789663)

Target: DIAPH1 (Diaphanous Homolog 1 (DIAPH1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIAPH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DIAPH1 Antibody

Binding Specificity: C-Term

Purpose: DIAPH1 Antibody - C-terminal region

Sequence: TGVMDSLLEA LQSGAAFRRK RGPRQANRKA GCAVTSLLAS ELTKDDAMAA

Predicted Reactivity: Cow: 85%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 92%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DIAPH1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63910-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DIAPH1

Target: DIAPH1 (Diaphanous Homolog 1 (DIAPH1))

Alternative Name: DIAPH1

Background:

Background Information: This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: Diaphanous homolog 1 (Drosophila)

Alternative Symbols: DIA1, DRF1, DFNA1, LFHL1, SCBMS, hDIA1

Protein Name: Protein diaphanous homolog 1

Molecular Weight: 141kDa

Gene ID: 1729

NCBI Accession: NP_005210

UniProt: O60610

Pathways: Sensory Perception of Sound