GIPR antibody (N-Term)
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- Target See all GIPR Antibodies
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GIPR antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GFVLRQCGSD GQWGLWRDHT QCENPEKNEA FLDQRLILER LQVMYTVGYS
- Predicted Reactivity
- Cow: 92%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against GIPR. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product GIPR Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 466 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- Alternative Name
- GIPR (GIPR Products)
- Synonyms
- GIPR antibody, PGQTL2 antibody, GIP-R antibody, Gm1081 antibody, Gm160 antibody, Gippr antibody, RATGIPPR antibody, gastric inhibitory polypeptide receptor antibody, glucagon receptor antibody, GIPR antibody, LOC100303705 antibody, Gipr antibody
- Background
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This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
Alias Symbols: MGC126722, PGQTL2
Protein Interaction Partner: LNX1, UBC, GIP,
Protein Size: 466 - Molecular Weight
- 53 kDa
- Gene ID
- 2696
- NCBI Accession
- NM_000164, NP_000155
- UniProt
- P48546
- Pathways
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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