KMO antibody (N-Term)

Catalog No. ABIN2789698

The Rabbit Polyclonal anti-KMO antibody (ABIN2789698) specifically detects KMO in WB. The antibody is reactive with Human, Mouse, Rat, Horse, Rabbit, Cow and Guinea Pig samples.

Quick Overview for KMO antibody (N-Term) (ABIN2789698)

Target: KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KMO antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KMO Antibody

Binding Specificity: N-Term

Purpose: KMO Antibody - N-terminal region

Sequence: RLLKCNPEEG MITVLGSDKV PKDVTCDLIV GCDGAYSTVR SHLMKKPRFD

Predicted Reactivity: Cow: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 85%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against KMO. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human KMO

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64019-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KMO

Target: KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

Alternative Name: KMO

Background:

Background Information: This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease.

Gene Name: kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

Alternative Symbols: dJ317G22.1

Protein Name: Kynurenine 3-monooxygenase

Molecular Weight: 49kDa

Gene ID: 8564

UniProt: O15229