PRKAG3 antibody (N-Term)
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- Target See all PRKAG3 Antibodies
- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PRKAG3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ENSSSWPSPA VTSSSERIRG KRRAKALRWT RQKSVEEGEP PGQGEGPRSR
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PRKAG3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PRKAG3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 489 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
- Alternative Name
- PRKAG3 (PRKAG3 Products)
- Synonyms
- Ampkg3 antibody, prkag3-a antibody, PRKAG3 antibody, AMPKG3 antibody, AMPKg3L antibody, AMPKg3S antibody, Amkg3 antibody, protein kinase AMP-activated non-catalytic subunit gamma 3 antibody, protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b antibody, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit antibody, Prkag3 antibody, PRKAG3 antibody, prkag3.S antibody, prkag3-b antibody
- Background
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The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
Alias Symbols: AMPKG3
Protein Interaction Partner: BAG3, KLC1, CRYAB, NGRN, LMCD1, PRKAA1, PRKAB2, PRKAB1,
Protein Size: 489 - Molecular Weight
- 54 kDa
- Gene ID
- 53632
- NCBI Accession
- NM_017431, NP_059127
- UniProt
- Q9UGI9
- Pathways
- AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effect
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