GMDS antibody (C-Term)

Catalog No. ABIN2789736

The Rabbit Polyclonal anti-GMDS antibody (ABIN2789736) specifically detects GMDS in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio) samples.

Quick Overview for GMDS antibody (C-Term) (ABIN2789736)

Target: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMDS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GMDS Antibody

Binding Specificity: C-Term

Purpose: GMDS Antibody - C-terminal region

Sequence: WEGKNENEVG RCKETGKVHV TVDLKYYRPT EVDFLQGDCT KAKQKLNWKP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against GMDS. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64110-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GMDS

Target: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Alternative Name: GMDS

Background:

Background Information: GDP-mannose 4,6-dehydratase catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans.

Gene Name: GDP-mannose 4,6-dehydratase

Alternative Symbols: GMD, SDR3E1

Protein Name: GDP-mannose 4,6 dehydratase Ensembl ENSP00000436726

Molecular Weight: 39kDa

Gene ID: 2762

NCBI Accession: NP_001240775

UniProt: E9PI88