ITGA2 antibody (C-Term)

Catalog No. ABIN2789791

The Rabbit Polyclonal anti-ITGA2 antibody is suitable to detect ITGA2 in samples from Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Horse and Rabbit. It has been validated for WB and IF.

Quick Overview for ITGA2 antibody (C-Term) (ABIN2789791)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ITGA2 Antibody

Binding Specificity: C-Term

Purpose: ITGA2 Antibody - C-terminal region

Sequence: LQNLQNQASL SFQALSESQE ENKADNLVNL KIPLLYDAEI HLTRSTNINF

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ITGA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ITGA2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64290-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: ITGA2

Background:

Background Information: This gene product belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.

Gene Name: Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

Alternative Symbols: BR, GPIa, CD49B, HPA-5, VLA-2, VLAA2

Protein Name: Integrin alpha-2

Molecular Weight: 126kDa

Gene ID: 3673

NCBI Accession: NP_002194

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex