ORC5 antibody (C-Term)

Catalog No. ABIN2789793

This Rabbit Polyclonal antibody specifically detects ORC5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig and Rabbit.

Quick Overview for ORC5 antibody (C-Term) (ABIN2789793)

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ORC5 Antibody

Binding Specificity: C-Term

Purpose: ORC5 Antibody - C-terminal region

Sequence: TRKLWRNIEP HLKKAMQTVY LREISSSQWE KLQKDDTDPG QLKGIRGSIE

Predicted Reactivity: Cow: 100%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ORC5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64293-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ORC5

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Alternative Name: ORC5

Background:

Targeted Subunit: 5

Background Information: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene Name: Origin recognition complex, subunit 5

Alternative Symbols: ORC5L, ORC5P, ORC5T, PPP1R117

Protein Name: Origin recognition complex subunit 5

Molecular Weight: 37kDa

Gene ID: 5001

NCBI Accession: NP_859531

UniProt: O43913

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA