CDC40 antibody (N-Term)

Catalog No. ABIN2789853

The Rabbit Polyclonal anti-CDC40 antibody (ABIN2789853) specifically detects CDC40 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio) samples.

Quick Overview for CDC40 antibody (N-Term) (ABIN2789853)

Target: CDC40 (Cell Division Cycle 40 (CDC40))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC40 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDC40 Antibody

Binding Specificity: N-Term

Purpose: CDC40 Antibody - N-terminal region

Sequence: NQGLTVFETG QKKTEKRKKF KENDASNIDG FLGPWAKYVD EKDVAKPSEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CDC40. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64500-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC40

Target: CDC40 (Cell Division Cycle 40 (CDC40))

Alternative Name: CDC40

Background:

Background Information: Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.

Gene Name: Cell division cycle 40 homolog (S. cerevisiae)

Alternative Symbols: EHB3, PRP17, PRPF17

Protein Name: Pre-mRNA-processing factor 17

Molecular Weight: 65kDa

Gene ID: 51362

NCBI Accession: NP_056975

UniProt: O60508

Pathways: Ribonucleoprotein Complex Subunit Organization